Institute of Communication and Computer Systems

The In Silico Oncology Group (ISOG) is a leading research entity in the field of multiscale cancer modelling and the emerging discipline of in silico oncology. A number of novel, primary 'top-down' clinically-driven simulation models have been developed, tested and disseminated by the Group. ISOG has founded the workshop series 'International Advanced Research Workshops on In Silico Oncology'. It also leads several actions related to in silico oncology in the running EC funded IP projects p-medicine, DRTHERAPATMyHealthAvatar and the EC funded EU-US project TUMOR. ISOG has also led in silico oncology related actions in the concluded EC funded projects ACGT (Advancing Clinicogenomic Trials on Cancer) and ContraCancrum.

The major responsibility of ICCS is to provide the overall scientific coordination of the project throughout its lifetime. Primary ICCS tasks also include a) leading the design and development of clinically driven cancer models and integrative hypermodels consisting of simpler and more manageable constituent component models and b) driving the development of hypermodel and data repositories. Another important task of ICCS is its contribution to the clinical adaptation and validation of the CHIC infrastructure, the development of the hypermodelling infrastructure and the dissemination and exploitation of the project’s results.

The development of the Hypermodelling Oncosimulator will serve as a demonstrator of implementation of the VPH hypermodelling concept in the cancer domain. In order to ensure the clinical orientation of the project, the clinical modeling paradigms of nephroblastoma, glioblastoma and lung cancer and the corresponding clinical trials/studies undertaken by the clinical partners will be adopted and addressed. In addition, the design of the repositories will be tailored to the clinical scenarios of the project, while being at the same time generic enough to be reusable by several different medical scenarios.

Team members

Photo of Research Professor Georgios Stamatakos Research Professor Georgios Stamatakos
Institute of Communication and Computer Systems
S.
Tel: +30 210 772 2287
Fax: +30 210 772 3557
Photo of Dr Dimitra Dionysiou Dr Dimitra Dionysiou
Institute of Communication and Computer Systems
Tel: +30 210 772 2287
Fax: +30 210 772 3557